A 92-year-old man presented with progressively worsening eye pain, diplopia on lateral gaze and blurred vision for the past 12 months. Radiological imaging confirmed a large left lacrimal gland lesion. The patient subsequently underwent a superio-lateral orbitotomy with left dacryoadenectomy and tumor removal, histopathology subsequently confirmed an epithelial-myoepithelial carcinoma arising ex pleomorphic adenoma of the lacrimal gland. Epithelial-myoepithelial carcinoma is a rare lacrimal gland tumour and the authors believe this case to be the first reported in the Australian population and associated with prolonged eye pain.
Adenoma, Pleomorphic , Carcinoma , Lacrimal Apparatus , Male , Humans , Aged, 80 and over , Adenoma, Pleomorphic/diagnostic imaging , Adenoma, Pleomorphic/surgery , Adenoma, Pleomorphic/pathology , Lacrimal Apparatus/diagnostic imaging , Lacrimal Apparatus/surgery , Lacrimal Apparatus/pathology , Eye Pain , Australia , Carcinoma/pathology
Melanoma incidence is increasing globally with Australia having the highest incidence in the world. Pregnancy-associated melanoma is recognized in the published work; however, significant knowledge deficiencies exist. We present the case of a 34-year-old woman with dysplastic nevus syndrome who over a 15-year period developed a total of nine melanomas, with eight clustered around an 18-month peri- to post-partum period. The first eight lesions were in situ with the ninth lesion invasive. No metastatic disease was observed over the 18-year follow-up period. This case identifies the potential sensitivity of a subset of melanomas to pregnancy-related factors, with particular relevance to the development of lesions in the post-partum period. We suggest that patients with a history of any documented melanoma risk factors, particularly dysplastic nevus syndrome, require close monitoring especially during pregnancy and early post-partum.
Dysplastic Nevus Syndrome , Melanoma , Skin Neoplasms , Adult , Australia , Female , Humans , Melanoma/diagnosis , Melanoma/epidemiology , Pregnancy , Risk Factors , Skin Neoplasms/diagnosis , Skin Neoplasms/epidemiology